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. 2013 Feb 28;8(2):e57431. doi: 10.1371/journal.pone.0057431

Table 3. In vivo effects of Reishi on the expression of PI3K/AKT/mTOR pathway genes.

Gene Complete name Fold change P value
EIF4B Eukaryotic translation initiation factor 4B −1.4 0.03
GJA1 Gap junction protein, alpha 1, 43kDa −2.9 0.01
NFKBIA Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.5 0.04
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 −1.3 0.03
PDK1 Pyruvate dehydrogenase kinase, isozyme 1 −1.7 0.01
RPS6K1 Ribosomal protein S6 kinase,70kDa,polypeptide 1 −1.9 0.02

Only genes that demonstrated −1.3>1.3-log2 fold difference and P<0.05 from RT2 PCR arrays are shown.