Table 3. In vivo effects of Reishi on the expression of PI3K/AKT/mTOR pathway genes.
| Gene | Complete name | Fold change | P value |
| EIF4B | Eukaryotic translation initiation factor 4B | −1.4 | 0.03 |
| GJA1 | Gap junction protein, alpha 1, 43kDa | −2.9 | 0.01 |
| NFKBIA | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 1.5 | 0.04 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | −1.3 | 0.03 |
| PDK1 | Pyruvate dehydrogenase kinase, isozyme 1 | −1.7 | 0.01 |
| RPS6K1 | Ribosomal protein S6 kinase,70kDa,polypeptide 1 | −1.9 | 0.02 |
Only genes that demonstrated −1.3>1.3-log2 fold difference and P<0.05 from RT2 PCR arrays are shown.