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. 2008 Jun;294(6):R1777–R1789. doi: 10.1152/ajpregu.00056.2008

Fig. 4.

Fig. 4.

Increase in muscle atrogin-1 and MuRF1 mRNA after oral ingestion of alcohol. Top: representative RPA of atrogin-1, MuRF1, and L32 in gastrocnemius from male, fed rats administered 75 mmol/kg of alcohol via oral gavage. Middle: quantitation of all RPA data from rats administered alcohol by oral gavage where values are expressed as means ± SE for n = 6 or 7 rats per group. *P < 0.05 compared with time-matched control value. Bottom: quantitation of all RPA data determined on gastrocnemius of chronic (12–14 wk) alcohol-fed rats in which values are expressed as means ± SE for n = 10–12 per group.