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. 2013 Jan 25;43(2):119–153. doi: 10.3109/10408444.2012.756455

Table 5.

Air exposure levels corresponding to toxicological endpoints for the general public.

Agency/guideline Critical effect Endpoint Uncertainty factor Guideline value Reference
Non-cancer
USEPA RfC Decreased lymphocyte count in workers BMCL = 8.2 mg/m3 300 3 × 10−2 mg/m3 USEPA (2003)
EU risk assessment report Decreased lymphocyte count in workers NOAEC = 3.2 mg/m3 None 3.2 mg/m3 European Chemicals Bureau (2008)
Cancer
USEPA Leukemia in workers Low-dose linearity utilizing maximum likelihood estimates Not applicable 1 × 10−5 risk (1.3–4.5 µg/m3) USEPA (2003)
European Commission Air Quality Standards 5 µg/m3 http://ec.europa.eu/environment/air/quality/standards.htm

BMCL = the 95% lower bound on the benchmark concentration. NOAEC = no observed adverse effect concentration.