Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Mar 22;62(3):358–367. doi: 10.1136/gutjnl-2012-302103

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: http://creativecommons.org/licenses/by-nc/2.0/ and http://creativecommons.org/licenses/by-nc/2.0/legalcode.

PMC Copyright notice

H pylori up-regulates MMP-1 in a protein kinase C (PKC)-dependent manner. BIS I-treated or non-treated AGS cells were incubated with H pylori P12 wt, PMA (A–D) or H pylori P1 wt or the cagA and virB7 mutants (E, F) for 3 h or for the indicated periods of time. MMP-1 expression was analysed by qRT-PCR (A, C, E) or immunoblotting (B, D, F). The graphs in (B) summarise the densitometric analysis of three independent immunoblots (experiments). GAPDH, occludin and histone H3 were immunodetected to show the appropriate fractionation and equal protein amounts in the cell samples. Bacterial lysate was used as a negative control. *p<0.05, **p<0.01 versus non-stimulated cells; #p<0.05, ##p<0.01 versus BIS I-free stimulated cells.