Table 4.
Comparison of the risk of pre-eclampsia for groups of Asian and African origin and the majority population in European countries
| Author, year, (reference number) | Study design | Study population | Variable | Ethnic groups | n | Results | Comments | |
|---|---|---|---|---|---|---|---|---|
| Khalil et al. 2012 (62) | Prospective cohort study | Pregnant women in 3 hospitals in South England, UK | Pre-eclampsia, defined affording to International Society for the Study of Hypertension in Pregnancy (ISSHP) |
N Caucasian Afro-Caribbean South Asian East Asian Mixed |
76,158 57,564 11,395 3,645 1,793 1,761 |
1,698 cases (2.3%)ab | Unadjusted OR (ref) 2.91 (2.62–3.24) 1.58 (1.28–1.95) 1.03 (0.72–1.47) 1.23 (0.89–1.72 |
Data collected as part of routine antenatal care. Number of cases in subgroups not reported. Significantly higher OR for pre-eclampsia in Afro-Caribbean and South Asian than Caucasian women |
| Bouthoorn et al. 2012 (78) | Population-based prospective cohort study | Pregnant women, The Generation R Study, Rotterdam, the Netherlands, 2002–2006 | Pre-eclampsia, defined according to ISSHP |
N Dutch Turkish Moroccan Cape Verde Surinamese-Creolec Surinamese-Hindustan |
6,215 3,886 718 534 331 232 250 |
120 cases (2.1%)a 1.9% 1.6% 0.8% 4.2% 2.4% 3.8% |
Unadjusted OR (ref) 0.83 (0.44–1.57) 0.40 (0.14–1.10) 2.22 (1.22–4.07) 1.24 (0.5–3.11) 2.04(1.00–4.13) |
4–11% missing values for hypertensive pregnancy complications in ethnic groups |
a
Figures calculated based on number of cases reported in the paper.
b
Figures in subgroups not reported.
c
Results for the Surinamese, who are reported to have at least partly African (the Creoles) and Indian (the Hindustanis) ancestral origin are given in this table, but not for women from the Antilles.