Table 3.
Effect of intervention on secondary outcome measures
| ParkFit | Controls | Estimated difference (95% CI)* | P value | ||||
|---|---|---|---|---|---|---|---|
| No | Effect of intervention | No | Effect of intervention | ||||
| Activity diary—median (interquartile range) hours/week | |||||||
| Baseline | 297 | 5.5 (3.1-10.3) | 282 | 6.3 (3.3-10.5) | |||
| 6 to 24 months | 276 | 7.6 (4.7-12.4) | 276 | 6.9 (4.2-10.8) | |||
| Mean change | 275 | 1.3 | 273 | 0.5 | 30% (17% to 45%) | <0.001 | |
| Activity monitor—median (interquartile range) kcal/day | |||||||
| Baseline | 273 | 453 (368-618) | 269 | 462 (346-604) | |||
| 6 to 24 months | 269 | 504 (390-667) | 269 | 440 (355-582) | |||
| Mean change | 254 | 38.7 | 258 | −14.2 | 12% (7% to 16%) | <0.001 | |
| Quality of life—mean (SD) Parkinson’s disease questionnaire (PDQ-39) | |||||||
| Baseline | 297 | 26.0 (13.7) | 286 | 26.2 (13.1) | |||
| 6 to 24 months | 278 | 26.4 (13.7) | 277 | 27.7 (12.7) | |||
| Mean change | 278 | 0.1 | 276 | 1.7 | −0.9 (−2.1 to 0.3) | 0.14 | |
| Physical fitness—mean (SD) six minute walk test (6MWT) | |||||||
| Baseline (distance in m) | 298 | 391.6 (87.5) | 283 | 392.9 (84.5) | |||
| 12 and 24 months | 256 | 404 (95.1) | 256 | 394.4 (86.5) | |||
| Mean change | 255 | 8.4 | 253 | −1.6 | 4.8 (0.1 to 9.6) | 0.05 | |
*Estimated (relative) difference, based on analysis of covariance.