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Relaxation responses induced by MEPY in endothelium-intact rat aortic rings pre-contracted with phenylephrine (PE, 1 μM) in the presence or absence (control) of indomethacin (1 μM) or atropine (1 μM) in Krebs-Henseleit solution. The relaxant effects of MEPY on isolated rat aortic rings were calculated as a percentage of the contraction in response to PE. Values are expressed as mean ± SEM (n = 4–8).
