Table 2.
miRNAs having substitutions at the GGU motif
| miRNAs | Canonical sequence* | Modified reads | Percentage |
|---|---|---|---|
| tgu-let-7a |
UGAGGUAGUAGGUUGUAUAGUU |
11500 |
5.5% |
| tgu-let-7b |
UGAGGUAGUAGGUUGUGUGGUU |
1629 |
6.7% |
| tgu-let-7c |
UGAGGUAGUAGGUUGUAUGGUU |
1556 |
5.2% |
| tgu-let-7d |
AGAGGUAGUAGGUUGCAUAGUU |
395 |
5.5% |
| tgu-let-7e |
UGAGGUAGUAGAUUGAAUAGUU |
3864 |
5.2% |
| tgu-let-7f |
UGAGGUAGUAGAUUGUAUAGUU |
12490 |
5.1% |
| tgu-let-7i |
UGAGGUAGUAGUUUGUGCUGUU |
3792 |
8.2% |
| tgu-miR-122 |
UGGAGUGUGACAAUGGUGUUUG |
6211 |
14.0% |
| tgu-miR-133b |
UUGGUCCCCUUCAACCAGCUAU |
18 |
5.1% |
| tgu-miR-140 |
ACCACAGGGUAGAACCACGGAC |
674 |
5.0% |
| tgu-miR-15a |
UAGCAGCACAUAAUGGUUUGU |
382 |
5.4% |
| tgu-miR-15c |
UAGCAGCACAUCAUGGUUUGU |
187 |
5.4% |
| tgu-miR-181b |
AACAUUCAUUGCUGUCGGUGGGU |
254 |
6.2% |
| tgu-miR-183 |
UAUGGCACUGGUAGAAUUCACU |
5 |
5.1% |
| tgu-miR-18a |
UAAGGUGCAUCUAGUGCAGAUA |
228 |
12.5% |
| tgu-miR-18b |
UAAGGUGCAUCUAGUGCAGUU |
7 |
5.0% |
| tgu-miR-196 |
UAGGUAGUUUCAUGUUGUUGGG |
8 |
10.0% |
| tgu-miR-221 |
AGCUACAUUGUCUGCUGGGUUUC |
2636 |
6.4% |
| tgu-miR-222 |
AGCUACAUCUGGCUACUGGGUCUC |
1413 |
6.5% |
| tgu-miR-2970 |
GACAGUCAGCAGUUGGUCUGG |
219 |
11.7% |
| tgu-miR-363 |
AAUUGCACGGUAUCCAUCUGU |
83 |
6.8% |
| tgu-miR-383 |
CAGAUCAGAAGGUGAUUGUGGC |
101 |
7.3% |
| tgu-miR-456 |
CAGGCUGGUUAGAUGGUUGUC |
34 |
7.8% |
| tgu-miR-458 |
AUAGCUCUUGGAAUGGUUCUGC |
31 |
5.1% |
| tgu-miR-551 | GCGACCCAUACUUGGUUUCAG | 69 | 5.0% |
*The seed regions (2–8th nucleotides) are underlined. The GGU motifs are marked in boldface.