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Artemis phosphorylation is delayed following high LET damage. Western blots were probed for total Artemis protein and mobility shifts of the protein indicate phosphorylation has occurred. Blots are shown 2 h post X-ray or iron nuclei exposure (A, left and right panel respectively) and 48 h post X-ray or iron nuclei exposure (B, left and right panel respectively). Arrows indicate location of basally-phosphorylated Artemis (lower arrow) and hyper-phosphorylated Artemis (upper arrow).
