Table 2. Relationship between tumor p53 status and annual household income in the adjusted analysis.
Adjusted logistic regression** OR (95% CI) (n = 143) | OR (95% CI) additionally adjusted for smoking (n = 136) | OR (95% CI) further adjusted for age, education, and BMI (n = 131) | |
Odds of acquiring a p53 mutation with increasing household income* | 1 | 1 | 1 |
0.42 (0.18 to 0.97) | 0.4 (0.17 to 0.94) | 0.32 (0.10 to 0.99) | |
Odds of acquiring a p53 IHC-positive tumor with increasing household income* | |||
1 | 1 | 1 | |
0.57 (0.30 to 1.08) | 0.63 (0.33 to 1.21) | 0.88 (0.40 to 1.97) |
OR = odds ratio; CI = confidence interval; IHC = immunohistochemistry
Trend test. Shown is the OR for the stepwise increase in household income (reference: low income). Income coded as 0 (< $15,000), 1 ($15,000 to $60,000), and 2 (> $60,000); adjustments: smoking (pack years), age, and body mass index (BMI) were used as continuous data; other covariates were dichotomized for the analysis, as shown in Table 1
adjusted for race/ethnicity, node status, tumor estrogen receptor status, and tumor grade