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Suggested treatment continuums for metastatic colorectal cancer using (a) intensive or (b) less intensive therapy.[54] 5-FU = fluorouracil; FOLFIRI = irinotecan plus infusional fluorouracil/leucovorin; FOLFOX = oxaliplatin plus infusional fluorouracil/leucovorin; LV = leucovorin. * indicates that cetuximab may be administered alone for patients intolerant to irinotecan. Reproduced from Goldberg et al.,[54] copyright 2007, with permission of AlphaMed Press, Inc.
