Table 1.
Patient and treatment characteristics (n = 91)
| n (%); or mean ± SDd; or median; IQRe | |
|---|---|
| Patient characteristics | |
| Male gender | 34 (37.4) |
| Age, in years | 59.1 ± 15.0 |
| Body mass index, in kg/m2 | 24.7; 22.7–27.3 |
| CIRS scorea | 22.0 ± 3.8 |
| Diagnostic category, according to axis 1 of DSM-IV-Rc: | |
| Depressive disorder without psychotic features | 50 (54.9) |
| Depressive disorder with psychotic features | 24 (26.4) |
| Bipolar disorder, depressive episode | 14 (15.4) |
| Other disordersb | 3 (3.3) |
| Documented or clinically suspected personality disorder present, according to axis 2 of DSM-IV-R | 27 (29.7) |
| MADRSf score at baseline (n = 88) | 36.2 ± 8.6 |
| MMSEg score at baseline (n = 86) | 28; 25–29 |
| Treatment characteristics | |
| Had previous course(s) of ECT | 28 (30.8) |
| Days between last ECT and index ECT (n = 28) | 646; 202–1,393 |
| Use of seizure threshold influencing concomitant pharmacotherapy: | |
| Benzodiazepines | 54 (59.3) |
| Antiepileptics | 7 (7.7) |
| Antidepressants | 52 (57.1) |
| Antipsychotics | 58 (63.7) |
| Electrode placement is bifrontotemporal at first titration session | 28 (30.8) |
| Initial seizure threshold, in millicoulombs | 60.9 ± 42.3 |
| Dynamic impedance at first titration session, in Ω | 275.5 ± 59.5 |
| Etomidate dose at first titration session, in mg | 20; 18–22 |
| Succinylcholine dose at first titration session, in mg | 80; 75–100 |
| Total number of ECT sessionsh (n = 86) | 17.9 ± 7.4 |
| Switch from right unilateral to bifrontotemporal electrode placement during coursei (n = 63) | 33 (52.4) |
aCumulative Illness Rating Scale
bSchizophrenia (n = 2) and malignant neuroleptic syndrome (n = 1)
cDiagnostic and Statistical Manual of Mental Disorders
dStandard deviation
eInterquartile range
f Montgomery–Åsberg Depression Rating Scale
gMini-Mental State Examination
hDropouts of treatment (suicide n = 1; terminal illness n = 1; wanted to stop n = 3) excluded from analysis
iOnly patients started with right unilateral electrode placement were analyzed