Table 3.
Outcome of the six controlled studies on vestibular schwannoma; all comparing microsurgery (MS) and radiosurgery (RS)
| Author publication ear | Therapy FU (no.) | Follow-up (range) | Mortality (%) | 2nd ther. (%) | Facial intact* (%) | % useful hearing† | Other complications‡ | Hospital days | Work resume (%) | QoL tests§ | QoL (% results) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Pollock 200610 | MS 36 RS 46 |
3.5 year mean (1–5.2 year) |
0 0 |
0 4 |
83 98 |
5 63 |
33 11 |
? ? |
? ? |
DHI, HS, HSQ |
↓ =* |
| Myrseth 200911 | MS 28 RS 60 |
≥2 year | 0 0 |
18 2 |
82 100 |
0 68 |
14 0 |
12,5 2.5 |
100 93 |
SF36, GBI | SF36= GBI ↑ |
| Pollock 199512 | MS 40 RS 47 |
3 year median (2.1–4 year) |
0 0 |
0 0 |
78 91 |
14 75 |
38 13 |
9,5 1.4 |
? ? |
ANSPQ | ↓ 45 ↓ 26 |
| Myrseth 200515 | MS 86 RS 103 |
5.9 year mean (1–14.2 year) |
1 0 |
6 5 |
80 95 |
5 32 |
47 4 |
? ? |
? ? |
SF36, GBI | ↓ =* |
| Regis 200214 | MS 110 RS 97 |
≥3 year | 1 0 |
9 3 |
67 100 |
36 50 |
41 8 |
23 3 |
66 99 |
Pellet | ↓ 39 ↓ 9 |
| Karpinos 200213 | MS 18 RS 49 |
4 year median (0.3–7 year) |
0 0 |
0 4 |
60 97 |
40 44 |
48 5 |
2–16 1–2 |
88 94 |
None | – – |
Bold: significantly better.
*Percentage preserved, House-Brackmann grade 1–2.
†Percentage preserved, AAO-HNS class A–B or Gardner–Robertson grade I–II.
‡Percentage complications as new trigeminal deficit, haemorrhage, cerebrospinal fluid (CSF) leakage, meningitis, wound infection, CSF-shunt needed.
§Quality of life (QoL) from questionnaires as Dizziness Handicap Inventory, Headache Survey, Health Status Questionnaire, ShortForm36, Glasgow Benefit Inventory, Acoustic Neuroma Association Patient Questionnaire, Pellet Questionnaire.