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Shown are the structures of a) PLL/PLL-DOTA, and b) PLL/PLL-DTPA random copolymers. C) The coupling reaction used to conjugate the PLL-DOTA macromolecular contrast agent to human serum albumin (HAS).8–10 Adapted with permission from Seiving, P. F.; Watson, A. D.; Rocklage, S. M.; Bioconjugate Chem. 1990, 1, 65–71.8
