Table 1.
Sex-specific distributions of demographics, variables involved in the estimation of arterial elasticity, endothelial and inflammation markers, and lung function: The MESA Study, 2000–2002.
| Characteristics | Female (N=1832) | Male (N=1803) | |||
|---|---|---|---|---|---|
| Mean or % | SD | Mean or % | SD | p-value | |
| Age (yr) | 65.3 | 9.7 | 65.4 | 9.8 | 0.73 |
| Race/ethnicity | |||||
| White (column %) | 35 | 36 | 0.68 | ||
| Chinese (column %) | 16 | 17 | |||
| Black (column %) | 25 | 25 | |||
| Hispanic (column %) | 24 | 23 | |||
| Height (cm) | 159.2 | 7.2 | 172.8 | 7.5 | <0.001 |
| Heart rate (beats/min) | 64.9 | 9.6 | 62.0 | 10.1 | <0.001 |
| Systolic blood pressure (mmHg) | 124.1 | 21.2 | 124.8 | 17.9 | 0.32 |
| Diastolic blood pressure (mmHg) | 68.5 | 10.0 | 75.1 | 8.9 | <0.001 |
| Hypertension (%≥140/90/Rx) | 45 | 45 | 1.00 | ||
| Body mass index (kg/m2) | 28.5 | 6.2 | 27.7 | 4.5 | <0.001 |
| Waist (cm) | 97.1 | 16.0 | 99.0 | 12.4 | <0.001 |
| Cigarette smoking | |||||
| Current (%) | 11 | 14 | <0.001 | ||
| Former (%) | 26 | 46 | |||
| Median | IQR | Median | IQR | ||
| Endothelial Marker | |||||
| sICAM-1, ng/mL | 266.8 | 228.8–310.3 | 263.5 | 226.0–305.0 | 0.56 |
| Inflammatory/Hemostatic marker | |||||
| Fibrinogen, mg/dL | 350 | 306.5–400 | 320 | 282.0–367.0 | <0.001 |
| General Inflammatory Markers | |||||
| hs-C-reactive protein (CRP), mg/L | 2.4 | 0.9–5.4 | 1.3 | 0.7–2.8 | <0.001 |
| Interleukin-6 (IL-6), pg/mL | 1.2 | 0.8–1.9 | 1.1 | 0.7–1.7 | 0.001 |
| Mean or % | SD | Mean or % | SD | ||
| Arterial elasticity | |||||
| Large artery elasticity (ml/mmHg*10) | 12.0 | 5.0 | 15.3 | 5.5 | <0.001 |
| Small artery elasticity (ml/mmHg*100) | 3.9 | 2.4 | 5.4 | 3.1 | <0.001 |
| Lung Function | |||||
| Forced Vital Capacity (FVC) (mL) | 2590 | 612 | 3813 | 842 | <0.001 |
| Forced Expiratory Volume (FEV1) (mL) | 1978 | 497 | 2806 | 701 | <0.001 |
| FEV1/FVC Ratio (%) | 76.0 | 8.0 | 74.0 | 9.0 | <0.001 |
BMI, body mass index; sICAM-1, soluble intercellular adhesion molecule; hs-CRP, high sensitive C-reactive protein; IL-6, Interleukin-6; Rx = treatment for hypertension; IQR, Inter-quartile range; FVC, Forced Vital Capacity; FEV, Forced expiratory volume in 1 second; FEV1/FV, Ratio of FEV1 to FVC; LAE, large artery elasticity; SAE, small artery elasticity; SD, standard deviation; SVR, systemic vascular resistance
Sample size for sICAM-1: 805 women and 675 men; for IL-6 1800 women and 1755 men