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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Neuropharmacology. 2012 Jul 15;64:348–356. doi: 10.1016/j.neuropharm.2012.07.016

Fig. 1.

Fig. 1

Dose-response study of nicotine-induced locomotor activity in WT and DAT KO mice. Total ambulatory activity for 60 min after administration of saline (sal), 0.3 mg/kg nicotine (Nic 0.3 mg), 1 mg/kg nicotine (Nic 1 mg), or nicotine (Nic 3 mg) were indicated. Values represent mean ± SEM. *p = 0.05, compared with WT sal; ***p < 0.001 compared with DAT KO sal; ###p < 0.001 compared with WT sal; ##p < 0.005 compared with WT nicotine 1 mg; #p < 0.05 compared with WT nicotine 3 mg. N = 8–12 per treatment condition per genotype (male N = 4–8, female N = 4–7).