. Author manuscript; available in PMC: 2013 Sep 1.

Published in final edited form as: J Affect Disord. 2012 Mar 2;140(1):57–65. doi: 10.1016/j.jad.2012.01.031

Table 3.

Multilevel meta-analysis of response rates in medication treatment cells based on ITT data.

Variable	Model 1		Model 2		Model 3
Variable	Coefficient (SE)	Odds ratio (CI)	Coefficient (SE)	Odds ratio (CI)	Coefficient (SE)	Odds ratio (CI)
Intercept	0.40 (0.10)^*	1.49 (1.21–1.83)^*	0.061 (0.12)	1.06 (0.83–1.36)	−0.14 (0.14)	0.87 (0.65–1.15)
Comparator	–	–	0.63 (0.17)^*	1.87 (1.32–2.66)^*	0.63 (0.16)^*	1.88 (1.35–2.61)^*
Eightwks	–	–	–	–	0.40 (0.17)	1.49 (1.06–2.10)
Twelvewks	–	–	–	–	0.50 (0.30)	1.65 (0.89–3.06)
Variance component	0.349		0.243		0.206
−2LL	163.0		158.9		156.4
df	36		35		33

‘Comparator’ = dummy variable coded ‘1’ for comparator trials and ‘0’ for placebo-controlled trials. ‘Eightwks’ = dummy variable coded ‘1’ for 8 week duration trials and ‘0’ for all others. ‘Twelvewks’ = dummy variable coded ‘1’ for 12 week duration trials and ‘0’ for all others.

p<0.05.