Table 1.
Body weight, heart weight/body weight ratio, hematological, and serum biochemical parameters [mean (standard deviation)] obtained from Wistar rats by the end of the experimental period.
| Groups | ||||
|---|---|---|---|---|
| Parametersa | Control | Doxorubicin | Doxorubicin + stem cells |
Doxorubicin + C. sinensis |
| Body weight (g) | 264.8(31.1) | 133.3(22.0)* | 203.0(54.8)*† | 117.3(28.7)* |
| Hw / Bw ratio (×103) | 3.9(0.4) | 4.7(0.1)* | 3.5(0.6) | 5.3(0.8)* |
| RBC (×106/µl) | 6.1(0.6) | 6.9(2.4) | 5.9(0.3) | 5.7(0.1) |
| WBC (×103/µl) | 6.3(3.4) | 7.2(5.5) | 5.8(3.6) | 8.7(3.3) |
| CK (U/l) | 1565(2291) | 1079(439) | 1103(300) | 949(648) |
| CK-MB (U/l) | 752(675) | 619(90) | 536(466) | 528(530) |
| LDH (U/l) | 755(650) | 625(465) | 814(207) | 448(357) |
| Urea (mg/dl) | 54(9) | 40(15) | 22(18) | 39(3) |
| Creatinine (mg/dl) | 0.5(0.04) | 1.7(2.2) | 0.7(0.5) | 0.5(0.06) |
a
Hw / Bw ratio: heart weight/body weight ratio; RBC: red blood cell count; WBC: white blood cell count; CK: creatine kinase; CK-MB: creatine kinase isoenzyme; LDH: lactate dehydrogenase;
*
p < 0.05 vs. Control;
†
p < 0.05 vs. Doxorubicin