. Author manuscript; available in PMC: 2014 Jul 1.

Published in final edited form as: NMR Biomed. 2012 Sep 27;26(7):781–787. doi: 10.1002/nbm.2870

Table 1.

The summary of optical properties, photoisomerization, and r₁ relaxivity change of spiropyran– and spirooxazine–based activatable Gd CAs.

Light-responsive Gd CAs	Absorption	Absorbance value			Reversibility	r₁ relaxivity (mM⁻¹•s⁻¹)
		Dark	Light	Change		Dark	Light	Change
Spiropyran–Gd–DO3A	468 nm	1.09	0.37	66%	Yes	3.72	2.93	21%
Dinitrospiropyran–Gd–DO3A	502 nm	0.69	0.14	80%	Yes	2.51	2.05	14%
Spirooxazine–Gd–DO3A	440 nm	0.84	0.64	24%	No	5.58	5.93	6%