Table 1.
Correlation between clinicopathological characteristics and NDRG2 expression
| NDRG2(∓) | NDRG2(++) | NDRG2(+++) | P | |
|---|---|---|---|---|
| Age | 0.397 | |||
| ≤65 | 57 (62.0) | 22 (23.9) | 13 (14.1) | |
| >65 | 48 (51.6) | 38 (40.9) | 7 (7.5) | |
| Gender | 0.401 | |||
| Male | 66 (54.5) | 41 (33.9) | 14 (11.6) | |
| Female | 39 (60.9) | 19 (29.7) | 6 (9.4) | |
| pT | 0.038 | |||
| pT1 | 22 (64.7) | 4 (11.8) | 8 (23.5) | |
| pT2 | 41 (46.1) | 39 (43.8) | 9 (10.1) | |
| pT3–4 | 42 (67.8) | 17 (27.4) | 3 (4.8) | |
| pN | 0.900 | |||
| pN0 | 41 (55.4) | 24 (32.4) | 9 (12.2) | |
| pN1 | 39 (59.1) | 20 (30.3) | 7 (10.6) | |
| pN2–3 | 25 (55.6) | 16 (35.6) | 4 (8.9) | |
| pM | 0.605 | |||
| pM0 | 85 (55.9) | 50 (32.9) | 17 (11.2) | |
| pM1 | 20 (60.6) | 10 (30.3) | 3 (9.1) | |
| Vascular invasion | 0.036 | |||
| No | 46 (50.0) | 32 (34.8) | 14 (15.2) | |
| Yes | 59 (63.4) | 28 (30.1) | 6 (6.5) | |
| Tumor grade | 0.039 | |||
| 1–2 | 43 (51.2) | 25 (29.8) | 16 (19.0) | |
| 3 | 62 (61.4) | 35 (34.6) | 4 (4.0) | |
| Tumor size(cm) | 0.026 | |||
| ≤3.8 | 45 (48.9) | 34 (37.0) | 13 (14.1) | |
| >3.8 | 60 (64.5) | 26 (28.0) | 7 (7.5) | |
| Histologic type | 0.763 | |||
| Squamous cell carcinoma | 43 (59.7) | 22 (30.6) | 7 (9.7) | |
| Adenocarcinoma | 50 (55.6) | 30 (33.3) | 10 (11.1) | |
| Small-cell lung cancer | 12 (52.2) | 8 (34.8) | 3 (13.0) |
pT1 tumor size ≤3 cm, pT2 tumor size >3 cm, pT3–4 invasion outside of the lung
pN0 no lymph node metastasis, pN1 ipsilateral lymph node metastasis, pN2–3 contralateral lymphatic metastasis
pM0 no distant metastasis, pM1 distant metastasis