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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Jan 10;33(3):645–651. doi: 10.1161/ATVBAHA.112.300491

Table 2.

Progression of coronary artery calcification (CAC) quantity was modified by MGP Thr83Ala (additive model). Linear mixed effects model results for log(CAC quantity+1) among 605 Epidemiology of Coronary Artery Calcification Study participants.

Covariate Model I* Model II†
β±se P β±se P
Time (years) −0.23±0.03 <0.001 −0.25±0.04 <0.001
MGP −0.03±0.09 0.759 −0.02±0.09 0.851
Time*MGP 0.02±0.01 <0.001 0.02±0.01 0.001

MGP, matrix Gla protein; β, parameter estimate; se, standard error; Thr, threonine; Ala, alanine

*

Adjusted for sex, baseline age, a time-by-age interaction term and a time-by-sex interaction term.

†

Additionally adjusted for systolic blood pressure (SBP), a time-by-SBP interaction term, smoking status, a time-by-smoking status interaction term, total cholesterol, high-density lipoprotein cholesterol, antihypertensive medication use and abdominal obesity.