Table 2.

Criteria for high-risk cutaneous squamous cell carcinoma [12, 22, 24–26].

Histopathologic factors
Size >2 cm
High-risk location (head and neck)
In-transit metastatic lesion
Poor differentiation
Perineural invasion
Tumour thickness >5-6 mm
Desmoplastic growth
Other factors
Radiation field
Patients with immunosuppression (transplantation and others)
Recurrence
Multiple SCCs
Marjolin's ulcer (carcinoma in burn scar or chronic ulcer)