Table 2.
Associations of three congtive function tests with total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, non- high-density lipoprotein cholesterol, total cholesterol to high-density lipoprotein cholesterol ratio, low-density lipoprotein to high-density lipoprotein cholesterol ratio and trigriceride to high-density lipoprotein ratio
| Unadjusted |
Adjusteda |
Adjustedb |
|
|---|---|---|---|
| OR (95% CI) | OR (95% CI) | OR (95% CI) | |
| Japanese version of the Mini-Mental State Examination (J-MMSE) | |||
| TC | 1.003 (0.992 - 1.013) | 0.999 (0.987 - 1.012) | 1.000 (0.987 - 1.013) |
| HDL-C | 1.007 (0.980 - 1.034) | 0.998 (0.967 - 1.030) | 1.003 (0.970 - 1.037) |
| LDL-C | 1.003 (0.991 - 1.016) | 1.003 (0.989 - 1.017) | 1.002 (0.988 - 1.017) |
| Non-HDL-C | 1.002 (0.991 - 1.013) | 1.000 (0.987 - 1.012) | 0.999 (0.986 - 1.012) |
| TC/HDL-C ratio | 1.001 (0.666 - 1.504) | 0.988 (0.629 - 1.551) | 0.935 (0.584 - 1.497) |
| DLL-C/HDL-C ratio | 1.030 (0.618 - 1.718) | 1.060 (0.601 - 1.869) | 0.991 (0.549 - 1.789) |
| TG/HDL-C ratio | 0.966 (0.743 - 1.257) | 0.909 (0.681 - 1.212) | 0.882 (0.648 - 1.200) |
| Verbal Fluency Initial Letter (VFL) | |||
| TC | 1.003 (0.993 - 1.014) | 1.003 (0.992 - 1.015) | 1.003 (0.990 - 1.015) |
| HDL-C | 1.011 (0.984 - 1.037) | 1.011 (0.983 - 1.041) | 1.003 (0.970 - 1.036) |
| LDL-C | 1.005 (0.993 - 1.017) | 1.005 (0.993 - 1.018) | 1.005 (0.991 - 1.019) |
| Non-HDL-C | 1.002 (0.991 - 1.012) | 1.002 (0.990 - 1.013) | 1.002 (0.990 - 1.015) |
| TC/HDL-C ratio | 0.980 (0.659 - 1.457) | 0.936 (0.616 - 1.424) | 1.038 (0.663 - 1.626) |
| LDL-C/HDL-C ratio | 1.076 (0.656 - 1.764) | 1.044 (0.620 - 1.758) | 1.152 (0.660 - 2.012) |
| TG/HDL-C ratio | 0.862 (0.656 - 1.131) | 0.811 (0.609 - 1.081) | 0.884 (0.653 - 1.197) |
| Scenery Picture Memory Test (SPMT) | |||
| TC | 1.013 (1.002 - 1.024)c | 1.010 (0.998 - 1.022) | 1.007 (0.994 - 1.020) |
| HDL-C | 1.023 (0.996 - 1.050) | 1.009 (0.980 - 1.039) | 1.005 (0.974 - 1.036) |
| LDL-C | 1.019 (1.006 - 1.032)e | 1.019 (1.005 - 1.033)e | 1.017 (1.002 - 1.031)c |
| Non-HDL-C | 1.010 (0.999 - 1.021) | 1.008 (0.996 - 1.021) | 1.006 (0.994 - 1.019) |
| TC/HDL-C ratio | 0.964 (0.647 – 1.438) | 1.019 (0.662 - 1.568) | 1.033 (0.650 - 1.643) |
| LDL-C/HDL-C ratio | 1.217 (0.741 - 1.997) | 1.387 (0.810 - 2.374) | 1.402 (0.791 - 2.485) |
| TG/HDL-C ratio | 0.661 (0.473 - 0.925)c | 0.629 (0.444 - 0.889)d | 0.641 (0.444 - 0.925)c |
TC = total cholesterol, HDL-C = high-density lipoprotein cholesterol, LDL-C = low-density lipoprotein cholesterol, TG = triglyceride
Adjusted for age, gender and years of education
Adjusted for age, gender, years of education, use of lipid-lowering drugs, history of stroke and heart diseases, hypertension, diabetes, and current smoking and alcohol drinking status
p < 0.05
p < 0.01
p-value significant after Bonferroni adjustment