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. Author manuscript; available in PMC: 2013 Mar 3.
Published in final edited form as: Ann N Y Acad Sci. 2009 Oct;1177:30–38. doi: 10.1111/j.1749-6632.2009.05038.x

TABLE 1.

Genes Containing Iron Response Elements

Gene symbol UTR Protein name Proposed function
ALAS25 5′ 5′ aminolevulinic acid synthase Heme synthesis
APP41 5′ Amyloid precursor protein Alzheimer’s disease pathogenesis
CDC14A18 3′ Cell division cycle homolog A Phosphatase; cell cycle
DMT15 3′ Divalent metal transporter 1 Iron import
EPAS127 5′ HIF-2α Hypoxia-induced transcription
FTH5 5′ Ferritin heavy chain Iron storage
FTL5 5′ Ferritin light chain Iron storage
mACO18 5′ Mitochondrial aconitase Citrate-isocitrate conversion
SLC40A15 5′ Ferroportin Iron export
SNCA42 5′ Alpha-synuclein Synucleinopathy pathogenesis
TFRC5 3′ Transferrin receptor 1 Cellular iron uptake