Fig. 3.
Lack of Phl p 5-specific IgE and IgG1 in Phl p 5-chimeric mice. Allergen-specific IgE and IgG1 levels in sera of recipients of Phl p 5-transduced BM (n = 10), sera of recipients of GFP-transduced BM (n = 4) and sera of non-transplanted immunized mice (n = 5), were demonstrated before (pre imm), and after BMT (week 9,12,15,37 and 44) and analysed by ELISA. Mean antibody levels (+SD) are shown for each group. (a) Left panel: Phl p 5-specific IgE levels. Right panel: Bet v 1-specific IgE levels. (b) Left panel: Phl p 5-specific IgG1 levels. Right panel: Bet v 1-specific IgG1 levels. P-values for Phl p 5-specific IgE and IgG1 in sera of recipients of Phl p 5-transduced BM vs. recipients of GFP-transduced BM are demonstrated.