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. 2013 Mar 4;3:1365. doi: 10.1038/srep01365

Table 4. Degrees of colocalization as fuzzy linguistic variables and the respective ranges of values of popular coefficients used to estimate colocalization, such as PPI, Rr, R, k1(k2), and m1(m2). Set includes just five different variables: “Very Weak”, “Weak”, “Moderate”, “Strong”, and “Very Strong”, which can be used by cell and molecular biologists as a community-wide standard for describing the results of quantitative colocalization studies. PPI was calculated using PPA software. Other coefficients were calculated using CoLocalizer Pro software (see Methods). See Fig. 1 for description of a Gaussian membership function and Tables 1,2,3 for details about steps leading to creation of this Table.

Degree of colocalization/fuzzy linguistic variable Value of coefficients Very Weak Weak Moderate Strong Very Strong
PPI 0 ~ 0.12 0.13 ~ 0.39 0.40 ~ 0.60 0.61 ~ 0.87 0.88 ~ 1.0
Rr −1.0 ~ −0.27 −0.26 ~ 0.09 0.1 ~ 0.48 0.49 ~ 0.84 0.85 ~ 1.0
R 0 ~ 0.49 0.50 ~ 0.70 0.71 ~ 0.88 0.89 ~ 0.97 0.98 ~ 1.0
k1(k2) 0 ~ 0.49 0.50 ~ 0.70 0.71 ~ 0.88 0.89 ~ 0.97 0.98 ~ 1.0
m1(m2) 0 ~ 0.54 0.55 ~ 0.77 0.78 ~ 0.94 0.96 ~ 0.98 0.99 ~ 1.0