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. 2013 Mar 4;3:1363. doi: 10.1038/srep01363

Figure 2. Analysis of adenovirus replication and infection parameters under RNAi knockdown conditions.

Figure 2

(a) Adenoviral early and late RNA expression levels upon infection of HEK293 cells with viruses Bwtp19ΔE3 and AdΔfiberIL. Quantitative real-time PCR was performed using gene specific primers for early adenovirus genes E1B55K, DBP, E4Orf6 and late adenovirus genes fiber and hexon. *: p-value < 0.05. (b) Western Blot analysis for detection of viral early and late proteins after Bwtp19ΔE3 (P19) or AdΔfiberIL (ΔIL) infection. (c) Analysis of genome replication and particle production of an adenovirus deleted for virus-associated RNAs in the RNAi knockdown cell line B6 in comparison to HEK293 cells. *: p-value < 0.05. p.i: post-infection; h: hours.