Fig. 3.

Structural comparison of DNA-free and DNA-bound TAL repeats in dHax3. (A) DNA-free and DNA-bound dHax3 are shown for residues 323 to 675, which comprise TAL repeats 2 to 11. The two structures are superimposed by using the N-terminal 23 amino acids, which encompass helix a and the first half of helix b of TAL repeat 2. (B) Superimposition of TAL repeat 2 from DNA-free and DNA-bound dHax3. The structures are superimposed by using the first 23 amino acids. Only the main chains are shown. The orange circle highlights where the structures exhibit variations. (C) Interrepeat interactions in the DNA-bound dHax3. TAL repeats 2 and 3 are shown here. The H bonds and van der Waals interactions are shown in the left and right images, respectively. Water molecules are shown as red spheres, and H bonds are represented by red dashed lines. (D) Interrepeat interactions in the DNA-free dHax3.