Table 1.
Pharmacological effects of flowers from Rosa damascene
| Type of solution | Effect | Method of study | Reference |
|---|---|---|---|
| Extract( ethanolic , aqueous) | Hypnotic | Pentobarbital-induced sleep time | 43, 44 |
| Fraction(ethyl acetate, aqueous, n-butanol) | |||
| Extract (Hydroalcoholic , ethanolic ) | Analgesic | Hot plate , tail flick, acetic acid and formalin tests | 49, 50 |
| Essential oil | Anticonvulsant | Pentylenetetrazole and kindling methods | 62, 63 |
| Ethanolic and aqueous extracts | Antitussive | Citric acid method | 46 |
| Ethanolic extract , essential oil | Bronchodilatory | Tracheal chains | 66, 70 |
| Fraction(ethyl acetate, aqueous , n-butanol) | |||
| Aqueous-ethanolic extract | Potentiation of HR and contractility |
Isolated heart (Langendorff mode ) |
71 |
| Compounds purified from the methanol extract | Anti-HIV | Effect on C8166 and H9 cells infected with HIV | 33 |
| Essential oil and absolute extract | Antibacterial | Disk method, well-diffusion , microdilution method |
33, 77, 78 |
| Methanol extract | Anti-diabetic | Measurement of α-glucosidase activity | 73 |
| Extract (hydroalcohlic, ethanolic, fresh | Antioxidant | Measurement of free-radical-scavenging activity | 76, 83, 84 |
| flower, spent flower),essential oil | |||
| Boiled extract | Laxative and prokinetic | Frequency of defecation, Intestinal transit time | 78 |
| Hydroalcoholic extract | Anti-inflammatory | Rat paw edema induced by carrageenan | 85 |