Table 3.
Effect of orally administered CSE and CSB on blood glucose levels (mg/dl) of STZ-induced diabetic rats.
| Time (hr) |
0 | 1 | 2 | 3 | 4 | 8 | 216 |
|---|---|---|---|---|---|---|---|
| Groups | |||||||
| Gliben. 3 | 317±42 | 248±42 | 238±43 | 207±46** | 216±45* | 221±50 | 160±16*** |
| Neg. Ctrl. | 321±33 | 326±30 | 325±32 | 323±31 | 319±28 | 318±27 | 320±29 |
| CSHE 0.2 | 319±54 | 330±55 | 339±49 | 336±78 | 336±49 | 323±61 | 248±38** |
| CSHE 0.4 | 301±85 | 320±83 | 320±99 | 306±48 | 305±88 | 307±69 | 234±28*** |
| CSHE 0.8 | 332±49 | 349±54 | 339±57 | 337±20 | 335±46 | 285±10 | 212±22*** |
| CSBE 0.2 | 289±25 | 318±26 | 307±22 | 292±24 | 297±35 | 297±15 | 235±29*** |
| CSBE 0.4 | 283±42 | 305±31 | 304±30 | 293±46 | 285±44 | 274±43 | 178±29*** |
| CSBE 0.8 | 313±44 | 328±45 | 337±48 | 320±54 | 326±47 | 305±44 | 176±17*** |
Data has been shown as mean±SD. n= 6; * P< 0.05, ** P< 0.01, *** P< 0.001 denote significant difference compared to negative control (Neg. Ctrl.). One-way ANOVA followed by post hoc Bonferroni test,CSHE: Cucumis sativus hydroalcoholic extract (g/kg), CSBE: Cucumis sativus buthanolic extract (g/kg), Gliben.: Glibenclamide (3 mg/kg)