Table 1.
Parameters which change in the three scenarios; parameters values pre-surgery and for each hypothesis are show
| |
Pre-surgery |
Post-surgery |
Definition |
||
|---|---|---|---|---|---|
| |
|
Hypothesis |
|
||
| Parameters | Lower-intestinal (GLP-1) | Upper-intestinal (Anti-incretin) | Ghrelin | ||
| Nmeals |
1 |
1 |
1 |
1 |
meal n.1 is simulated |
| M1 |
500 |
500 |
500 |
500 |
amount of glucose in the meal |
| ATmin |
25 |
25 |
0 |
25 |
plasmatic anti-incretin basal level |
| Amax |
500 |
500 |
0 |
500 |
maximum amount of anti-incretin |
| HTmin |
150 |
150 |
150 |
0 |
plasmatic ghrelin basal level |
| Hmax |
300 |
300 |
300 |
0 |
maximum amount of ghrelin |
| Hmin |
29.6 |
29.6 |
29.6 |
0 |
minimum amount of ghrelin |
| kds |
0.02 |
0 |
0.02 |
0.02 |
transfer rate from stomach to duodenum |
| kls |
0 |
0.02 |
0 |
0 |
transfer rate from stomach to ileum |
| kld |
0.02 |
0 |
0.02 |
0.02 |
transfer rate from duodenum to ileum |
| kgd | 0.02 | 0 | 0.02 | 0.02 | transfer rate from duodenum to plasma glucose |