Table 2.
Morphologic findings by FSGS histologic subtype
| Morphologic Findings | Not Otherwise Specified | Tip | Collapsing | P Value |
|---|---|---|---|---|
| Total number of cases | 94 | 14 | 16 | — |
| Percent global glomerulosclerosis (n*) | 2.8 (0, 13) (92) | 0 (0, 0) | 0 (0, 7.7) | 0.05 |
| 2.8 (0, 13) (92) | 0 (0, 0) | — | 0.02 | |
| Percent segmental glomerulosclerosis (n*) | 13.8 (8.0, 25.0) (92) | 22.2 (9.1, 44.4) | 44 (26.5, 48.3) | <0.001 |
| 13.8 (8.0, 25.0) (92) | — | 44 (26.5, 48.3) | <0.001 | |
| — | 22.2 (9.1, 44.4) | 44 (26.5, 48.3) | 0.07 | |
| Percent any glomerulosclerosis (n*) | 20 (10.3, 40.0) (92) | 26 (9.5, 45.5) | 46.1 (29.2, 56.7) | 0.02 |
| Percent tubular atrophy/interstitial fibrosis | 10 (3, 25) | 5 (0, 5) | 20 (7.5, 70) | 0.003 |
| 10 (3, 25) | 5 (0, 5) | — | 0.03 | |
| 10 (3, 25) | — | 20 (7.5, 70) | 0.02 | |
| — | 5 (0, 5) | 20 (7.5, 70) | 0.001 |
All values are expressed as median percentage of glomeruli in a biopsy or median percentage of cortical area in a biopsy with the designated histologic finding (25th, 75th percentile); n* is the available n for a given value. Where not specified, the available n is the same as the total number of cases in the top row. P values are for Kruskal–Wallis rank sum three-way comparisons and selected two-way comparisons across histologic subtypes.