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. Author manuscript; available in PMC: 2014 May 15.
Published in final edited form as: Int J Cancer. 2012 Nov 26;132(10):2316–2326. doi: 10.1002/ijc.27924

Figure 1.

Figure 1

Human solid tumors preferentially lose small chromosomes. (a) Area-proportional Venn diagram indicating the numbers and fractions of a total of 19,003 human solid tumors that have lost, gained, concomitantly lost and gained or have neither lost nor gained whole-chromosomes. (b) Rates at which human solid tumors gain or lose individual whole-chromosomes. The blue bars indicate the means of the gain and loss rates. Chromosome 7 is gained significantly more frequently than any of the other chromosomes (p<0.01; two-sided Grubbs’ test). (c) Scatter plot of chromosome size in megabases (Mb) in relationship to the rate at which the chromosome is lost in human solid tumors. (d) Scatter plot of the number of genes on the chromosome in relationship to the rate at which the chromosome is lost in human solid tumors.