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Intestinal and extra-intestinal involvement. A 59-year-old woman with Grade IV graft-vs-host disease (GVHD). Patient died of GVHD. (a) Unenhanced scan shows the “water halo” sign in the large bowel (arrow). (b) Contrast-enhanced coronal reformation demonstrates large-bowel wall thickening and marked mucosal enhancement (thick white arrow). Gallbladder wall thickening (thin black arrow) and periportal oedema (thick black arrow) are seen as well.
