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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Eye Contact Lens. 2013 Jan;39(1):67–72. doi: 10.1097/ICL.0b013e31827c5b73

Figure 3.

Figure 3

Inflammation contributes to PA internalization in the rabbit corneal epithelium. Rabbits were fit with PMMA lenses for 24 hours in both eyes, followed by inoculation with PA and lens wear for an additional 24 hours. Treatment with DNase and D-Asp30 to dissolve scaffolds formed from necrotic neutrophil debris resulted in a significant reduction in internalized PA in the rabbit corneal epithelium in vivo; contralateral eye treated with vehicle only control (n=6, p=0.03). Figure adapted from Robertson et al., IOVS 2011;65 copyright IOVS.