Table 1.
Mean (s.d.) optimism scores by OXTR genotype
| Scale | n | OXTR rs53576
|
PADDb | PDOMb | |||
|---|---|---|---|---|---|---|---|
| GG | GA | AA | GA/AA | ||||
| Optimism 2004 | 1200 | 4.14 (0.77) | 4.19 (0.70) | 4.22 (0.71) | 4.20 (0.70) | 0.35 | 0.17 |
| Optimism 2008 | 1129 | 4.10 (0.73) | 4.10 (0.73) | 4.13 (0.75) | 4.11 (0.74) | 0.92 | 0.87 |
| Overall optimisma | 1229 | 4.10 (0.70) | 4.15 (0.65) | 4.16 (0.67) | 4.15 (0.66) | 0.49 | 0.24 |
| Optimistic outlook | 1228 | 4.05 (0.79) | 4.10 (0.74) | 4.08 (0.76) | 4.09 (0.74) | 0.54 | 0.29 |
| Pessimistic outlookc | 1228 | 4.17 (0.82) | 4.21 (0.80) | 4.23 (0.79) | 4.22 (0.80) | 0.54 | 0.29 |
| Optimisma | |||||||
| Age < 71 years | 584 | 4.15 (0.74) | 4.20 (0.65) | 4.08 (0.71) | 4.17 (0.67) | 0.34 | 0.75 |
| Age ≥71 years | 645 | 4.07 (0.67) | 4.10 (0.65) | 4.24 (0.62) | 4.13 (0.65) | 0.11 | 0.21 |
| < Bachelor degree | 834 | 4.08 (0.72) | 4.12 (0.66) | 4.12 (0.66) | 4.12 (0.66) | 0.77 | 0.47 |
| ≥Bachelor degree | 395 | 4.15 (0.67) | 4.21 (0.63) | 4.25 (0.69) | 4.22 (0.64) | 0.56 | 0.31 |
| Number of antidepressants | 1037 | 4.15 (0.70) | 4.18 (0.65) | 4.20 (0.63) | 4.19 (0.64) | 0.59 | 0.33 |
| Number of disease | 624 | 4.15 (0.68) | 4.23 (0.61) | 4.22 (0.62) | 4.22 (0.61) | 0.36 | 0.15 |
a
Mean of 2004 and 2008 optimism scores.
b
Results from analysis of variance assuming an additive (ADD) or dominant (DOM) genetic model.
c
High scores suggest low pessimism.