Table 3.

Calculated CMR_glc(ox) derived from neuronal activity in human visual cortex for OGI of 5.6

Behavioral state*	VGP	VGA	PRO	SEV	HAL	SLP	AWK
Σ(δi fi ηN,i) (×103 spike.neuron.cm/s per centimeter3)	282	1,192	1,317	1,306	1,959	2,674	3,407
Σ(δi fi ηN,i)/Σδj (×107 spike.neuron/s per centimeter3)	0.12	0.51	0.56	0.56	0.83	1.14	1.45
Ens = Σ Pns,x × ηN,x (×1017 ATP/s per centimeter3)	0.29	0.29	0.29	0.29	0.29	0.29	0.29
Es = Ps × Σ(δi fi ηN,i)/Σδj (×1017 ATP/s per centimeter3)	0.06	0.24	0.27	0.27	0.40	0.55	0.70
Etot = Ens + Es (×1017 ATP/s per centimeter3)	0.35	0.54	0.56	0.56	0.69	0.84	0.99
calcCMRglc(ox) (μmol/g per minute)	0.10	0.15	0.16	0.16	0.20	0.24	0.28
measCMRglc(ox) (μmol/g per minute)	0.08	0.14	0.15	0.14	0.18	0.24	0.31

Details in Calculations. To convert the EEG data in Table S2 into units of Σ(δ_i f_i η_N,i)/Σδ_j, simple conversions were needed with Eq. 6. The calculated CMR_glc(ox) [calcCMR_glc(ox)] was determined from Eq. 3. The measured CMR_glc(ox) [measCMR_glc(ox)] was determined from Eq. 4 assuming OGI of 5.6. AWK, awake; HAL, halothane; PRO, propofol; SEV, sevoflurane; SLP, non-REM sleep; VGA, acute vegetative; VGP, persistent vegetative.

*Details in SI Text, section 1 and see Fig. 1A for comparison between calcCMRglc(ox) and measCMRglc(ox).