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(A) Time spent immobile in the tail suspension test after physostigmine-induced immobility and its reversal by fluoxetine; n = 9–12 per group. (B) AChE activity in microdissected brain regions following chronic treatment with fluoxetine; n = 5 per group. (C) Time spent immobile in the tail suspension test following an acute bilateral infusion of physostigmine into the hippocampus; n = 7–12 per group. #P = 0.07; *P < 0.05; ***P < 0.001. All data are expressed as mean ± SEM.
