Fig. 7.

Effect of recipient or donor age on homing of BMDACs to burn wounds. BMDACs from donor male C57BL/6J mice were administered by tail vein injection 48 h after burn wounding of recipient female C57BL/6J mice. Normal skin and burn wound were harvested 8 h after injection. DNA was extracted and BMDAC homing was measured using qPCR for the Y chromosome-specific Sry gene relative to the autosomal Nme1 gene. Homing was expressed as the signal ratio from burn wound/normal skin. Mean±SEM (n=3–6 each) is shown. Statistical significance was assessed by two-way ANOVA with Bonferroni post hoc comparisons. *P<0.01 vs young recipients. a BMDACs from young (Y) donors were injected into Y or old (O) recipients. b BMDACs from Y or O donors were injected into Y recipients