Table 1.
Characteristics: Patients with Type 1 Diabetes Mellitus Stratified by Transplant Type
| Variable | Kidney Transplantation (n = 6212) | Simultaneous Pancreas-Kidney Transplantation (n = 4933) | P value |
|---|---|---|---|
|
| |||
| Pre-Transplantation Fracture (%) | 2.2 | 1.8 | 0.1 |
|
| |||
| Age at transplantation in years (SD) | 46.0 (10.9) | 40.4 (8.1) | <0.0001 |
|
| |||
| Female Gender (%) | 41 | 39 | 0.02 |
|
| |||
| Race (%) | |||
| White | 79.3 | 83.7 | <0.0001 |
| Black | 14.7 | 12.7 | 0.002 |
| Asian | 1.3 | 0.8 | 0.02 |
| Other | 4.7 | 2.7 | <0.0001 |
|
| |||
| BMI in kg/m2 (SD) | 26.7 (5.6) | 24.8 (5.7) | <0.0001 |
| BMI < 18.5(%) | 1.9 | 2.5 | 0.03 |
| BMI 18.5–24.9 (%) | 34.0 | 47.7 | <0.0001 |
| BMI 25–30 (%) | 29.5 | 28.4 | 0.2 |
| BMI 30–50 (%) | 19.9 | 9.1 | <0.0001 |
| Missing (%) | 14.7 | 12.4 | <0.0001 |
|
| |||
| Mean HLA-A, HLA-B, and HLA-DR mismatches (SD) | 2.4 (1.7) | 1.3 (1.2) | <0.0001 |
| 0 mismatches (%) | 14.2 | 26.8 | <0.0001 |
| 1–2 mismatches (%) | 38.2 | 59.2 | <0.0001 |
| 3–4 mismatches (%) | 32.7 | 11.1 | <0.0001 |
| 5–6 mismatches (%) | 13.8 | 1.8 | <0.0001 |
|
| |||
| Deceased Donor (%) | 48 | 100 | <0.0001 |
|
| |||
| Pre-Transplant Dialysis (%) | 78.4 | 80.9 | 0.001 |
|
| |||
| Years on Pre-Transplant Dialysis (SD) | 2.4 (2.1) | 2.0 (1.7) | <0.0001 |
|
| |||
| Parathyroidectomy (%) | 1.8 | 1.0 | <0.0001 |
|
| |||
| Corticosteroid Maintenance Immunosuppression (%) | 79.6 | 80.0 | 0.6 |
|
| |||
| Year of Transplant - Number (%) | |||
| 2000 | 835 (53.5) | 725 (46.5) | |
| 2001 | 895 (55.6) | 715 (44.4) | |
| 2002 | 941 (57.5) | 696 (42.5) | |
| 2003 | 821 (55.4) | 660 (44.6) | |
| 2004 | 992 (59.0) | 688 (41.0) | |
| 2005 | 894 (55.3) | 723 (44.7) | |
| 2006 | 834 (53.5) | 726 (46.5) | |