Table 2.

Multivariable Hazard Ratios: Patients with Type 1 Diabetes who received either Kidney or Simultaneous Pancreas-Kidney Transplantation

	Men (N=6690)				Women (N=4455)
	Hazard Ratio	95% CI		P-value	Hazard Ratio	95% CI		P-value
Simultaneous Pancreas-Kidney Transplantation	0.69	0.53	0.88	0.003	0.95	0.71	1.26	0.7
Pre-KTx Fracture	4.13	2.64	6.45	<0.0001	2.62	1.48	4.63	0.0009
Age at transplantation (per year over 18)	1.01	1.00	1.03	0.02	1.03	1.02	1.05	<0.0001
Race				-
White		Reference				Reference
Black	0.94	0.67	1.33	0.9	0.52	0.33	0.81	0.004
Asian	0.52	0.13	2.08	0.5	-	-	-	-
Other	0.96	0.51	1.83	0.9	0.91	0.42	1.96	0.8
BMI in kg/m2				-
BMI < 18.5	2.08	1.12	3.86	0.02	1.79	0.98	3.27	0.06
BMI 18.5–24.9		Reference				Reference
BMI 25–30	0.75	0.58	0.97	0.03	1.09	0.79	1.49	0.6
BMI > 30–50	0.62	0.43	0.90	0.01	1.02	0.70	1.48	0.9
Missing	0.79	0.56	1.11	0.2	1.20	0.82	1.76	0.3
Mean HLA-A, HLA-B, and HLA-DR mismatches (SD)				-
0 mismatches		Reference				Reference
1–2 mismatches	0.98	0.73	1.32	0.9	1.17	0.83	1.64	0.4
3–4 mismatches	1.13	0.82	1.57	0.5	0.93	0.62	1.40	0.7
5–6 mismatches	1.09	0.71	1.68	0.7	1.00	0.61	1.64	1.0
Pre-Transplant Dialysis	1.39	1.02	1.88	0.04	1.64	1.17	2.31	0.005
Parathvroidectomy				-
Pre- or Post-Transplant	0.32	0.04	2.26	0.6	1.33	0.88	3.03	0.5
Corticosteroid Maintenance Immunosuppression	1.08	0.76	1.54	0.7	0.81	0.56	1.17	0.3
Year				-
2000		Reference				Reference
2001	1.39	0.99	1.96	0.06	1.24	0.85	1.81	0.3
2002	0.93	0.63	1.38	0.7	1.09	0.72	1.65	0.7
2003	1.28	0.87	1.90	0.2	1.00	0.63	1.58	1.0
2004	1.15	0.75	1.77	0.5	0.87	0.53	1.43	0.6
2005	1.12	0.69	1.83	0.6	0.82	0.46	1.45	0.5
2006	1.60	0.93	2.76	0.09	1.00	0.51	1.93	1.0