Table 2.
Cytokines for diabetic and non-diabetic cases and controls (N=59)
| Variable | Controls | ESRD (Cases) |
||
|---|---|---|---|---|
| (N = 23) | All (N=36) | NonDM (N = 21) | DM (N = 15) | |
| Adiponectin (ug/ml) | 8.46 (4.70) | 15.66 (9) | 13.20 (8.01) | 19.13 (9.64) |
| p value | 0.001a | 0.001b | ||
| IL-6 (pg/ml)c | 2.9 [2.1, 2.9] | 6.2 [3.8, 10.4] | 5.3 [3.4, 6.7] | 7.9 [4.3, 16.0] |
| p value | 0.02a | <0.001b | ||
| PAI-1 (ng/ml) | 50.60 (19.7) | 44.63 (22.67) | 47.73 (25.1) | 40.30 (17.8) |
| p value | 0.30a | 0.30b | ||
| TNFα (pg/ml) | 10.17 (3.35) | 19.17 (12.14) | 21.12 (15.2) | 16.46 (4.88) |
| p value | 0.002 a | <0.001b | ||
| hsCRP (mg/dl) | 1.26 (0.94) | 4.16 (3) | 3.61 (2.94) | 4.94 (3.18) |
| p value | <0.001 a | <0.001b | ||
Continuous Variables: Mean (SD) or Geometric Mean [1st quartile, 3rd quartile]
a
t test: differences between controls and all cases.
b
ANOVA F-test: any groups different (3-way comparison test: controls vs nonDM cases vs DM cases)
c
Data natural log transformed: geometric means with [first quartile, third quartile] presented