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. 2013 Mar 4;8(3):e57958. doi: 10.1371/journal.pone.0057958

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© 2013 Huai et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A, HE staining (magnification×40) verified a typical histological character of BAVM. B, the immunohistochemical staining showed that MMP3 was localized mainly in the endothelial cell layer of BAVMs (arrows, magnification×200). C, MMP3 was strongly immunostained in neurons (triangle) but not in vascular structures (arrows, magnification×400).