Table 4. Cognitive performance dependent on familial longevity (offspring versus partner status^*).

	Offspring†	Partners†	Model 1			Model 2
Cognitive performance tests	N = 250	N = 250	β	95% CI	p	β	95% CI	p
15-PLT, correct pictures
trial 1	7.4 (0.11)	7.4 (0.12)	−0.13	−0.44, 0.18	0.40	−0.28	−0.63, 0.07	0.11
trial 2	10.4 (0.13)	10.3 (0.14)	−0.23	−0.56, 0.10	0.17	−0.30	−0.67, 0.07	0.11
trial 3	12.1 (0.12)	11.9 (0.12)	−0.32	−0.63, −0.01	0.042	−0.47	−0.80, −0.15	0.005
immediate recall	29.9 (0.31)	29.6 (0.33)	−0.69	−1.48, 0.10	0.088	−1.06	−1.92, −0.19	0.016
delayed recall	11.3 (0.14)	11.1 (0.14)	−0.42	−0.77, −0.07	0.020	−0.58	−0.98, −0.18	0.004
Stroop test, seconds
part 1	20.9 (0.38)	19.7 (0.34)	−1.27	−2.31, −0.23	0.017	−0.91	−2.13, 0.32	0.15
part 2	25.3 (0.33)	24.4 (0.30)	−0.86	−1.74, 0.02	0.057	−0.75	−1.77, 0.27	0.15
part 3	48.8 (0.86)	50.0 (0.97)	1.62	−0.67, 3.91	0.17	2.02	−0.56, 4.61	0.13
interference score	23.5 (0.74)	25.7 (0.84)	2.52	0.50, 4.54	0.015	2.84	0.57, 5.10	0.014
combined interference score	25.1 (0.92)	27.5 (1.02)	2.80	0.30, 5.30	0.028	3.12	0.21, 6.03	0.036
DSST‡, correct answers	46.3 (0.71)	46.2 (0.74)	−0.32	−2.16, 1.52	0.73	−0.82	−2.86, 1.21	0.43

^*Offspring = 0, partner = 1.

^†Values are expressed as mean (standard error).

^‡n = 223 for offspring and n = 223 for partners. Abbreviations: β, estimate; CI, confidence interval; 15-PLT, 15-Picture Learning Test; DSST, Digit Symbol Substitution Test. Model 1: adjusted for age, gender and years of education. Model 2: as model 1+ diabetes mellitus, cardiovascular diseases (myocardial infarction, stroke and hypertension), alcohol use, smoking, high-sensitivity C-reactive protein, interleukin-6 and apolipoprotein E genotype. Robust standard errors were used to account for familial relationships among the offspring.