Table 5. Cognitive performance expressed as number of subjects with mistakes dependent on familial longevity (offspring versus partner status*).
Offspring† | Partners† | Model 1 | Model 2 | |||||
Cognitive performance tests | N = 250 | N = 250 | OR | 95% CI | p | OR | 95% CI | p |
15-PLT‡ | ||||||||
trial 1 | 13 (5.2) | 15 (6.0) | 1.13 | 0.53, 2.44 | 0.75 | 1.33 | 0.48, 3.68 | 0.58 |
trial 2 | 15 (6.0) | 13 (5.2) | 0.89 | 0.41, 1.94 | 0.77 | 0.95 | 0.37, 2.45 | 0.92 |
trial 3 | 10 (4.0) | 10 (4.0) | 1.09 | 0.44, 2.71 | 0.85 | 0.81 | 0.29, 2.28 | 0.69 |
immediate recall | 24 (9.6) | 23 (9.2) | 0.94 | 0.51, 1.73 | 0.85 | 0.88 | 0.43, 1.82 | 0.74 |
delayed recall | 16 (6.4) | 19 (7.7) | 1.32 | 0.63, 2.76 | 0.47 | 1.28 | 0.55, 2.99 | 0.57 |
Stroop test‡ | ||||||||
part 2 | 12 (4.8) | 24 (9.6) | 2.10 | 1.02, 4.32 | 0.043 | 2.03 | 0.86, 4.82 | 0.11 |
part 3 | 56 (22.6) | 78 (31.3) | 1.64 | 1.08, 2.50 | 0.021 | 1.69 | 1.05, 2.70 | 0.029 |
Offspring = 0, partner = 1.
Values are expressed as number (%).
Subjects with no mistakes = 0, subjects with one or more mistakes = 1. Abbreviations: OR, odds ratio; CI, confidence interval; 15-PLT, 15-Picture Learning Test. Model 1: adjusted for age, gender and years of education. Model 2: as model 1+ diabetes mellitus, cardiovascular diseases (myocardial infarction, stroke and hypertension), alcohol use, smoking, high-sensitivity C-reactive protein, interleukin-6 and apolipoprotein E genotype. Robust standard errors were used to account for familial relationships among the offspring.