Figure 2. The effect of HLA-C mismatching on NK-mediated killing.

(A) Killing of NK cells cultured over night with 100 IU/ml of IL-2 tested in HLA-C matched and mismatched setting; (B) Individual NK cultures in matched and mismatched setting out of 3 performed. E:T ratios were 10∶1. Y axis denotes specific killing (%). Figure shows the mean of five independent experiments performed. **denotes statistical significance in t-tests of P = 0.01. Error bars represent SEM.