Table 1. HLA-C matched and mismatched NK donors and melanoma patients.

		HLA-A			HLA-B			HLA-C
		Allele 1	Allele 2	KIR-Ligand	Allele 1	Allele 2	KIR-Ligand	Allele 1	Allele 2	KIR-Lignad
				03 or 11			Bw4			C1	C2
Melanoma Mel008		2	2	NO	15	15	NO	3	3	YES	NO
Mismatched	HD04	1	3	YES	37	57	YES	6	6	NO	YES
	HD02	11	32	YES	41	57	YES	6	17	NO	YES
	HD20	30	31	NO	13	35	YES	4	6	NO	YES
	HD14	2	30	NO	41	44	YES	4	17	NO	YES
Matched	HD07	32	33	NO	14	39	NO	8	12	YES	NO
	HD12	2	2	NO	41	44	YES	7	16	YES	NO
	HD09	2	29	NO	14	44	YES	8	1	YES	NO
Melanoma Mel10		1	1	NO	35	35	NO	4	4	NO	YES
Mismatched	HD12	2	2	NO	41	44	YES	7	16	YES	NO
	HD09	2	29	NO	14	44	YES	8	1	YES	NO
	HD07	32	33	NO	14	39	NO	8	12	YES	NO
Matched	HD04	1	3	YES	37	57	YES	6	6	NO	YES
	HD02	11	32	YES	41	57	YES	6	17	NO	YES
	HD20	30	31	NO	13	35	YES	4	6	NO	YES
	HD14	2	30	NO	41	44	YES	4	17	NO	YES

The table shows the identity of each of the two alleles of HLA-A, HLA-B and HLA-C for two melanoma patients (Mel008 and Mel10) and seven healthy NK donors (depicted as “HD” followed by a serial number). The table indicates whether one of the HLA-A alleles or HLA-B alleles is a KIR-ligand (highlighted in gray). Similarly, the table indicates whether each HLA-C is of C1 or C2 subgroup, effectively classifying all patients to homozygotes of C1 or C2, or C1–C2 heterozygotes (highlighted in gray). The table is arranged to demonstrate melanoma-NK pairs that are either HLA-C matched or mismatched.