Table 5. Combined effects of polymorphisms of VDR on NSCLC survival.
| Combined Genotypes (Unfavorable Genotypes) | Patients | Deaths | MST (Months) | Crude HR (95% CIs) | Adjusted HR (95% CIs)* |
|---|---|---|---|---|---|
| 0 | 485 | 257 | 26.4 | 1.00 | 1.00 |
| 1 | 69 | 42 | 20.0 | 1.39 (1.01-1.93) | 1.54(1.10-2.14) |
| 2 | 14 | 12 | 17.4 | 2.16 (1.21-3.86) | 2.27(1.26-4.08) |
| Locus trend | P for trend = 0.003 | 1.44 (1.14-1.80) | 1.52(1.21-1.91) | ||
*Adjusted for age, gender, smoking status, stage, histology, surgical operation and chemotherapy or radiation treatment.