Table 3. Hemotological toxicity.
Dose number of level patients |
leukocytes |
Neutrophils |
Hemoglobin |
platelets |
|||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Grade (NCI Toxicity criteria) | |||||||||||||||||
1 | 2 | 3 | 4 | 1 | 2 | 3 | 4 | 1 | 2 | 3 | 4 | 1 | 2 | 3 | 4 | ||
1 | 3 | - | 1 | - | - | - | 1 | - | - | 1 | - | - | - | - | 1 | - | - |
2 | 6 | 1 | 2 | 3 | - | 1 | 2 | 3 | - | 2 | - | - | - | 1 | - | - | - |
3 | 5 | - | - | 3 | 2 | - | - | 3 | 2 | 2 | - | - | - | - | 2 | - | - |
Dose level, 1: level I; 2: level II; 3: level III