Table 1. Characteristics of children with chronic hepatitis B and of healthy controls.
Chronic hepatitis B | |||
HBeAg pos | HBeAg neg | Healthy controls | |
No of patients | 34 | 26 | 60 |
Male | 14 (41%) | 12 (46%) | 33 (55%) |
Female | 20 (59%) | 14 (54%) | 27 (45%) |
Age (years) | |||
Mean | 8.8 | 12.0 | 7.1 |
SD | 3.7 | 3.4 | 3.7 |
Race | |||
African | 4 | 6 | 1 |
Asian | 22 | 15 | 9 |
Caucasian | 8 | 5 | 50 |
ALT (U/l ref. value 5–45) | |||
Mean | 46.5 | 25.6 | 14.3 |
SD | 27.6 | 12.6 | 5.3 |
HBV DNA (IU/ml) | |||
Mean | 5.1E+08 | 8.5E+02 | NA |
SD | 1.2E+09 | 2.0E+03 | |
Genotypes | |||
A | 2 (6%) | 2 (8%) | |
B | 11 (32%) | 2 (8%) | |
C | 5 (15%) | 2 (8%) | |
D | 12 (35%) | 7 (27%) | |
E | 3 (9%) | 2 (8%) | |
F | 1 (3%) | 0 (0%) | |
N/A | 0 (0%) | 11 (42%) | 60 (100%) |
Footnote:
ALT: Alanine aminotransferase.
N/A: Not analysed.